第 45 卷第 4 期 Vol. 45 No. 4 2015 年 8 月 Aug 2015

所属栏目：农药及中间体 5%丙硫克百威缓释颗粒剂的制备及其缓释性能研究

李福星1，2，3，郭 军1，刘卫东2，3，李 涛2，3，李 敏2，3 （1. 湖南人文科技学院，湖南 娄底 417000；2. 湖南化工研究院有限公司 国家农药创制工程技术研究中心，湖南 长沙 410014；3. 农用化学品湖南省重点实验室，湖南 长沙 410014）

摘　要：以丙硫克百威为研究对象，研发出一种5%丙硫克百威缓释颗粒剂。采用界面聚合法，以聚脲异氰酸酯为壁材制备20%丙硫克百威微囊母液，加入填料、粘合剂将制备的丙硫克百威微囊母液制成5%丙硫克百威缓释颗粒剂。对20%丙硫克百威微囊母液的形态及粒径等进行了测定。对5%丙硫克百威缓释颗粒剂室内缓释性能进行了检测。结果表明：微囊粒径约为1~4 μm，分布均匀，包裹率为96.3%，载药量为18.6%。在pH=5缓冲液中释放时间为38 d，在pH=7缓冲液中释放时间为89 d。具有持效期长、环境友好、对环境适应性强、农药利用率高、对人、畜和害虫的天敌安全性高等优点，具有推广价值。

关键词：丙硫克百威；缓释颗粒剂；缓释；微囊

中图分类号：S482.3　　文献标识码：A　　文章编号：1009-9212（2015）04-0013-04

A Study on Preparation and Properties of 5% Benfuracarb Slow-release Granules

LI Fu-xing1,2,3, GUO Jun1, LIU Wei-dong2,3, LI Tao2,3, LI Min2,3 (1. Hunan University of Humanities, science and Technology, Loudi 417000, China; 2. National Engineering Research Center for Agrochemicals, Hunan Research Institute of Chemical Industry Co., Ltd., Changsha 410014, China; 3. Hunan Province Key Laboratory for Agrochemicals, Changsha 410014, China)

Abstract：The 20% benfuracarb microcapsules liquor was prepared by interfacial polymerization using PAPI as microcapsules wall material.The 5% benfuracarb sustained-release granules were prepared by fillers, adhesive, and 20% benfuracarb microcapsules liquor. The morphology and particle size of the microcapsules were characterized. The sustained-release performance and prevention effect to sugarcane soil pests of the 5% benfuracarb sustained-release granules were tested. The results showed that: the microcapsules particle size was about 1~4 μm; the encapsulation rates of benfuracarb was 96.3%; the drug loading of the microcapsules was 18.6%; release time was 38 days at pH=5 buffer and 89days at pH=7 buffer.

Key words：benfuracarb; sustained-release granules; slow-release; microcapsules

作者简介：李福星（1992-），男，湖南岳阳人，硕士研究生，主要从事农药剂型研究。

收稿日期：015-05-25