| 第 48 卷第 5 期 |  | Vol. 48 No. 5 | | 2018 年 10 月 | Oct 2018 |
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所属栏目：农药及中间体
十三吗啉的合成工艺研究 |
| 陈朋朋，周晓军，章奉良
（江苏莱科作物保护有限公司，江苏 南通 226400） |
| 摘 要：对十三吗啉的合成工艺路线进行了研究。通过二异丙醇胺环合脱水得到中间体2，6-二甲基吗啉，以十三醛作为原料，与中间体2，6-二甲基吗啉催化加氢得到目标产物十三吗啉。2步收率92%以上，方法合成未见报道，具有污染小、环境友好等特点，易于实现工业化生产。 |
| 关键词：十三吗啉；合成；加氢 |
| 中图分类号：TQ455 文献标识码：A 文章编号：1009-9212（2018）05-0014-03 |
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| Study on Sythesis of Tridemorph |
| CHEN Peng-peng, ZHOU Xiao-Jun, ZHANG Feng-liang
(Jiangsu Laike Crop Protection Co., Ltd., Nantong 226400, China) |
| Abstract：This study conducts a research on the synthesis process of tridemorph. The intermediate 2,6-dimethylmorpholine is obtained by dehydration of diisopropanolamine cyclization. By using tridecylic aldehyde as a raw material, the intermediate 2, 6-dimethylmorpholine as the catalyst, adding hydrogen, the tridemorph is obtained. The yield of tridemorph is above 92% with this two step. This method hasn't been reported in any domestic paper. Furthermore, the method has been characteristics of less pollution, enviromental protection and easy to realization of industrial production. |
| Key words：tridemorph; sythesis; hydrogenation |
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作者简介：陈朋朋（1986-），男，江苏南通人，工程师，研究方向：化工技术的研究与开发。
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收稿日期： 2018-09-1
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