| 第 49 卷第 6 期 |  | Vol. 49 No. 6 | | 2019 年 12 月 | Dec 2019 |
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所属栏目：功能材料
高品质戊基三联苯腈的制备及提纯 |
| 岳 刚，井 昭*，王利民，禹 凯，关登仕
（河北美星化工有限公司，河北 辛集 052360） |
| 摘 要：以4′-正戊基联苯硼酸和对氯苯腈为原料，经过Suzuki偶联制备了戊基三联苯腈。研究了碱和溶剂对反应转化率的影响，以及重结晶溶剂的选择。优化的反应条件为：碱为无水碳酸钾，反应溶剂为甲苯和N，N-二甲基甲酰胺，温度85~90℃，4 h转化率为96.3%，经二甲苯和乙醇（v∶v=10∶1）提纯后纯度大于99.9%（GC），收率高达70%。 |
| 关键词：Suzuki偶联；戊基三联苯腈；液晶中间体 |
| 中图分类号：TQ24 文献标识码：A 文章编号：1009-9212（2019）06-0064-03 |
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| Preparation and Purification of High-purity Pentyl Terphenyl Nitrile |
| YUE Gang, JING Zhao*, WANG Li－min, YU Kai, GUAN Deng－shi
(Hebei Maison Chemical CO., Ltd., Xinji 052360, China) |
| Abstract：The pentyl terphenyl nitrile was prepared by Suzuki coupling 4'-pentyl-4-biphenylboronic acid with p-chlorobenzonitrile. The effects of different bases and solvents on the conversion rate of the reaction and the choice of purification solvent were investigated. The optimum conditions for the reaction were determined: the base was potassium carbonate; the solvents were toluene and N,N-dimethylformamide; the conversion rate was 96.3% at 85~90℃ after 4 h; the purity after purification by xylene and ethanol (v∶v=10∶1) was more than 99.9%(GC) with the yield as high as 70% |
| Key words：Suzuki coupling; pentyl terphenyl nitrile; liquid crystal intermediate |
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作者简介：岳 刚（1973-），男，河北唐山人，主要从事液晶等显示材料方面的研究（E-mail：maisonyue@126.com）。
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联 系 人：井 昭，硕士，主要从事液晶单体及中间体的研究（E-mail：maisonjingzhao@126.com）。
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收稿日期：2019-12-03
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