第 51 卷第 4 期 Vol. 51 No. 4 2021 年 8 月 Aug 2021

所属栏目：功能材料 仿生促进杂化膜的制备及其性能研究

郭明钢1，米盼盼1，卞 冰2，王 畅1，杨晓航1* （1. 大连理工大学 盘锦产业技术研究院，辽宁 盘锦 124221；2. 沈阳鼓风机集团 辅机成套工程有限公司，辽宁 沈阳 110869）

摘　要：基于人工肺（ECMO）与血液直接接触，提出利用生物相容性良好的材料制备仿生促进杂化膜用于ECMO。在聚醚砜超滤膜上涂覆聚甲基丙烯酸甲酯作为分离层，氧载体选用钴卟啉与咪唑配位的仿血红素结构，制备了一种仿生促进杂化膜，重点考察其在低压环境下对氧气／二氧化碳及氧气／氮气的分离性能。气体渗透性测试结果表明：当聚甲基丙烯酸甲酯（PMMA）质量分数为4.6%、 四苯基钴卟啉质量分数为0.460%、压力为0.012 MPa时，制备的CoTPP-PMMA-PES复合膜分离性能较好，此时膜厚度为0.92 μm。与PMMA-PES复合膜相比，氧气渗透速率由8.05 GPU升至21.25 GPU，氧气／氮气选择性由1.28升至2.66，氧气／二氧化碳选择性由0.70升至0.92。

关键词：膜式氧合器；氧气分离；促进传递膜；钴卟啉；仿生

中图分类号：TB302　　文献标识码：A　　文章编号：1009-9212（2021）04-0048-06

Preparation and Properties of Biomimetic Transport Hybrid Membrane

GUO Ming-gang1, MI Pan-pan1, BIAN Bing2, WANG Chang1, YANG Xiao-hang1* (1. Panjin Institute of Industrial Technology, Dalian University of Technology, Panjin 124221, China; 2. Shenyang Blower Works Group Auxiliary Equipment Complete Engineering Co., Ltd., Shenyang 110869, China)

Abstract：Based on the direct contact between ECMO and blood, a biomimetic facilitated transport hybrid membrane with good bio-compatibility was proposed for ECMO. A biomimetic transport hybrid membrane was prepared by coating poly (methyl methacrylate) on polyethersulfone ultrafiltration membrane as separation layer and using cobalt porphyrin and imidazole as oxygen carrier. The separation performance of O2/CO2 and O2/N2 under low pressure was investigated.The results of gas permeability test showed that when the optimal concentration of PMMA was 4.6%, the concentration of Cobalt meso-tetraphenylporphine was 0.460%, and the pressure was 0.012 MPa, the separation performance of CoTPP-PMMA-PES composite membrane was the best, and the membrane thickness was 0.92 μm. Compared with pmma-pes composite membrane, O2 permeation rate increased from 8.05 GPU to 21.25 GPU, O2/N2 selectivity increased from 1.28 to 2.66, O2/CO2 selectivity increased from 0.70 to 0.92.

Key words：membrane oxygenator; oxygen separation; facilitated transport membrane; cobalt porphyrin; biomimic

作者简介：郭明钢（1987—），男，辽宁鞍山人，硕士研究生，研究方向：化工分离工程（E-mail：461759136@qq.com）。

收稿日期：2021-06-08