第 51 卷第 5 期 Vol. 51 No. 5 2021 年 10 月 Oct 2021

所属栏目：功能材料 1，3-双（2-噁唑啉基）苯的合成工艺优化

张 浩，曾桂钰，陶锡祺 （江西仰立新材料有限公司，江西 吉安 343000）

摘　要：以间苯二甲腈、乙醇胺为原料，无水醋酸锌或氯化锌为催化剂，合成了1，3-双（2-噁唑啉基）苯，优化了工艺条件。优化条件为：n（间苯二甲腈）∶n（乙醇胺）∶n（催化剂）=1.00∶4.00∶0.04，反应5 h，温度120~125 ℃。优化条件下，产品含量99.2%，反应收率94.7%，产品结构经核磁、红外和质谱确证。该工艺还提出了乙醇胺的回收方法，具有收率高、成本低、三废排放少等优势，宜于工业化生产。

关键词：噁唑啉；间苯二甲腈；乙醇胺

中图分类号：TQ25　　文献标识码：A　　文章编号：1009-9212（2021）05-0078-03

Process Optimization for the Preparation of 2,2'-(1,3-Phenylene) Bis-(2-oxazoline)

ZHANG Hao, ZENG Gui-yu, TAO Xi-qi (Jiangxi Univate New Material Co.,Ltd., Ji'an 343000, China)

Abstract：2,2'-(1,3-Phenylene)bis-(2-oxazoline) was prepared from 1,3-dicyanobenzene and ethanolamine using Zn(OAc)2 or ZnCl2 as catalyst. Process conditions were optimized and obtained as followings: the ratio of n(1,3-Dicyanobenzene)∶n(ethanolamine)∶n(catalyst) was of 1.00∶4.00∶0.04; reacting time was of 5 h; the reaction temperature was at a range from 120 ℃ to 125 ℃. The yield and purity of the product were reached up to 94.7% and 99.2%, respectively. The objective product was confirmed by 1H NMR, 13C NMR, IR and MS. The recovery of ethanolamine was also presented. This process has the advantages including high yield, low cost, less waste water and facile industrialization.

Key words：oxazoline; 1,3-dicyanobenzene; ethanolamine

作者简介：张 浩（1989—），男，安徽临泉人，工程师，博士，主要从事精细化工的工艺研发工作（E-mail：hao_zhang@cacch.com）。

收稿日期：2021-08-03