第 51 卷第 5 期 Vol. 51 No. 5 2021 年 10 月 Oct 2021

所属栏目：分析与测试 氯虫苯甲酰胺原药中甲磺酸的离子色谱测定

李楠楠，蒋 锋，覃柳琼 （上海晓明检测技术服务有限公司，上海 201612）

摘　要：采用离子色谱法测定了氯虫苯甲酰胺原药中甲磺酸的质量分数。试样用二氯甲烷溶解，纯水萃取，以5 mmol／L氢氧化钾溶液为淋洗液，选用IonPac AS11-HC阴离子色谱柱和电导检测器，外标法定量分析。结果显示，甲磺酸的色谱峰无其他峰干扰，方法在1.104 7~8.837 4 μg／mL浓度范围内的标准曲线线性回归系数为0.999 9，标准偏差为0.001 mg／kg，变异系数为0.82%，平均回收率为100.5%，定量限为0.005%。该方法可准确快速测定氯虫苯甲酰胺中的甲磺酸质量分数。

关键词：甲磺酸；氯虫苯甲酰胺原药；离子色谱；外标法

中图分类号：O657.7　　文献标识码：A　　文章编号：1009-9212（2021）05-0102-03

Determination of Methanesulfonic Acid in Technical Chlorantraniliprole by Ion Chromatography

LI Nan-nan, JIANG Feng, QIN Liu-qiong (GreenTech Laboratory Co.,Ltd., Shanghai 201612, China)

Abstract：A method fordetermining methanesulfonic acid in chlorantraniliprole TC by IC was established. In a typical process, sample was dissolved in dichloromethane and followed by extraction using water. The analysis was conducted under conditions including 5 mmol/L potassium hydroxide solution as eluent, IonPac AS11-HC column and electrical conductivity detector. Results indicated that the linear correlation coefficient is 0.999 9 in a range from 1.104 7 μg/mL to 8.837 4 μg/mL; the SD is 0.001 mg/kg, RSD was 0.82%; average recovery was 100.5% and LOQ was 0.005%. This method is suitable for the analysis of methanesulfonic acid content in chlorantraniliprole.

Key words：methanesulfonic acid; chlorantraniliprole techanical; external standard method

作者简介：李楠楠（1990—），女，安徽淮南人，硕士研究生，研究方向：农药原药及制剂的研发与质检（E-mail：nannan_li@greentechlab.cn）。

收稿日期：2021-08-03