第 52 卷第 2 期 Vol. 52 No. 2 2022 年 4 月 Apr 2022

所属栏目：农药及中间体 20%甲基嘧啶磷·高效氯氟氰菊酯微囊悬浮剂的制备

李 敏1，2，刘 伟1，2，吴 曼1，2，王胜得1，2，曾雪云1，2，陈 灿1，2 （1.湖南化工研究院有限公司 国家农药创制工程技术研究中心，湖南 长沙 410014；2.农用化学品湖南省重点实验室，湖南 长沙 410014）

摘　要：采用界面聚合法制备20%甲基嘧啶磷·高效氯氟氰菊酯微囊悬浮剂，筛选了乳化剂、分散剂及其他助剂，考察了芯壁比、乳化速度、固化温度等因素对微胶囊稳定性的影响，确定了20%甲基嘧啶磷·高效氯氟氰菊酯微囊悬浮剂的配方及其制备工艺条件：甲基嘧啶磷和高效氯氟氰菊酯溶解在有机溶剂中，以PM-200为囊材，芯壁比10∶1、10%乳化剂EL-20、2%分散剂SP-2700。高速搅拌乳化速度800 r/min，缓慢升温35 ℃ 1 h、45 ℃ 1 h、55 ℃ 2 h进行固化。固化结束后降低至室温，加入增稠剂、防冻剂，得到所需的微囊悬浮剂。该制剂性能指标检测合格，包覆率高，且微胶囊形态好，化学结构稳定，界面聚合工艺操作简便，条件温和，适合工业化生产。

关键词：甲基嘧啶磷；高效氯氟氰菊酯；微囊悬浮剂；界面聚合

中图分类号：S482.3　　文献标识码：A　　文章编号：1009-9212（2022）02-0008-05

Preparation of 20% Pirimiphos-methyl·λ-cyhalothrin Microcapsule Suspension

LI Min1,2, LIU Wei1,2, WU Man1,2, WANG Sheng-de1,2, ZENG Xue-yun1,2, CHEN Can1,2 (1. National Engineering Research Center for Agrochemicals, Hunan Research Institute of Chemical Industry Co.,Ltd., Changsha 410014, China; 2. Hunan Province Key Laboratory for Agrochemicals, Changsha 410014, China)

Abstract：20% Pirimiphos-methyl·λ-cyhalothrin microcapsule suspension was prepared by the interfacial polymerization method. The effects of emulsifiers, disperser and other additives, core-wall ratio, high speed emulsification and curing temperature on the formation of microcapsule were studied. The preparation conditions were obtained as following: cyclohexanone and solvent oil PM-200 were selected as solvents, the dosage of emulsifier EL-20 was 10% and the dosage of dispersant SP-2700 was 2%. The emulsification stirring speed was 800 r/min, slowly heated up at 35 ℃ for 1 h, 45 ℃ 1 h and 55 ℃ 2 h for curing. Then thickening agent and antifreezing agent were added for the preparation of the CS. The results of the formulation physical-chemical properties tests showed that all indexs of CS met the standards of CS. The entire processing conditions of interfacial polymerization are simple, mild, fast, and suitable for industry.

Key words：pirimiphos-methyl; λ-cyhalothrin; microcapsule suspension; interfacial polymerization

作者简介：李 敏（1987—），女，山东滨州人，助理研究员，硕士，研究方向：农药制剂加工技术研究（E-mail：limin_1011@163.com）。

收稿日期：2022-03-01