第 33 卷第 2 期 Vol. 33 No. 2 2003 年 4 月 Apr 2003

所属栏目：其它 2-(2,4-二氯苯基)-1,2-环氧己烷的合成

王宇; 陈明; 陈平; 胡艾希(湖南化工研究院精细所; 湖南大学化学化工学院; 410007; 410006)

摘　要：杀菌剂己唑醇中间体 2 ( 2 ,4 二氯苯基 ) 1,2 环氧己烷 ( 1)的合成步骤如下 :以 2 ,4 二氯苯基戊酮 ( 1)为原料 ,用硫叶立德 (CH3) 3S+ CH3SO- 4为环氧化试剂 ,在碱性条件下得到 ( 1) ,收率≥95 %,产品含量≥ 95 %,此合成工艺反应条件温和易控。

关键词：杀菌剂; 己唑醇; 2-（2; 4-二氯苯基）-1; 2-环氧己烷; 硫叶立德

中图分类号：TQ454.4　　文献标识码：A　　文章编号：1009-9212(2003)02-0016-02

Synthesis of 2-(2,4-dichlorophenyl)-1,2-epoxyhexane

WANG yu 1;2;CHEN Ming 1;CHEN Ping 1;HU Ai-xi 2.(1.Department of fine Chemistry;Hunan Research Institute of Chemical Industry;CHangsha;410007;China;2.College of Chemistry and Chemical Engineering;Hunan University;Changsha Hunan;410006;China)

Abstract：dichlorophenyl)-1,2-epoxyhexane(1) was synthesized according to the following procedures. Compound (1) was prepared by reaction of 2,4-dichlorophenylpentanone(2) with (CH 3) 3S +CH 3SO - 4 which as sulphonium yield under base condition. The yield is up to 95% and the purity is over 95%. The reaction is mild and easy to be controlled.

Key words：antifungal pesticide; hexaconazole; 2-（2; 4-dichlorophenyl）-1; 2-epoxyhexane; sulphonium ylide

收稿日期：2002-12-23

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