第 33 卷第 5 期 Vol. 33 No. 5 2003 年 10 月 Oct 2003

所属栏目：其它 三乙胺催化合成2,5-二巯基-1,3,4-噻二唑

聂国朝(襄樊职业技术学院科研处; 湖北襄樊)

摘　要：采用三乙胺作为催化剂 ,由二硫化碳和水合肼合成了 2 ,5 二巯基 1,3,4 噻二唑 ,产率从传统工艺的 82.50 %提高至 90.01% ,并探讨了三乙胺的催化机理。通过试验得到了该反应的优惠工艺条件 :反应温度为 80℃、n(水合肼 )∶n(二硫化碳 )∶n(氢氧化钾 ) =1.0∶3 5∶2 0、每摩尔水合肼需加三乙胺 4 0mg。同时用红外光谱鉴定了产物的结构 ,并进行了氮元素分析及熔点测定 ,结果均与理论值相符。实验结果表明 ,该合成方法是可行的 ,可以推广应用。

关键词：2,5-二巯基-1,3,4-噻二唑; 二硫化碳; 水合肼; 合成

中图分类号：TQ252.5　　文献标识码：A　　文章编号：1009-9212(2003)05-0032-03

The Synthesis of 2,5-Dimercapto-1,3,4-Thiadiazole Using Triethylamine as Catalyst

NIE Guo-chao.（Xiangfan Vocational and Technical College; Xiangfan Hubei 441021; China）

Abstract：Dimercapto-1,3,4-thiadiazole was prepared by using triethylamine as catalyst.Compared with the traditional synthesis techniques,using triethlamine as catalyst,the reaction yield can be raised from 82.50% to 90.01%. The catalytic mechanism was studied and the optimal reaction conditions were investigated by the experiments. The optimum material ratio of n(hydrazine hydrate):n(carbon disulfide):n(KOH) is 1.0∶3.5∶2.0, suitable reaction temperature is 80℃, and triethylamine 40?mg is required. The construction o...

Key words：Dimercapto-1,3,4-thiadiazole; carbon disulfide; hydrazine hydrate; synthesis

收稿日期：2003-08-06

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