| 第 33 卷第 5 期 |  | Vol. 33 No. 5 | | 2003 年 10 月 | Oct 2003 |
|
所属栏目：其它
2-氯-6-氟甲苯的合成研究 |
| 刘丽荣; 王跃君; 张所信; 周海兵; 徐永章(淮海工学院化工系; 河北经贸大学附中; 江苏连云港; 河北石家庄) |
| 摘 要：研究了 2-氯-6-氟甲苯的合成。以铁粉为还原剂 ,在 100℃回流的情况下 ,于氯化亚铁水溶液中将原料 2-氯-6-硝基甲苯还原成 2-氯-6-氯基甲苯 ,根据Balz schieman反应 ,再由2-氯-6-氨基甲苯在工业乙醇溶液中重氮化生成氟硼酸重氮盐 ,最后氟硼酸重氮盐于 140℃分解得到产物 2-氯-6-氟甲苯 ,总收率为 67-98%。产品经气相色谱检测 ,纯度为 99-2%。 |
| 关键词：2-氯-6-硝基甲苯; 2-氯-6-氟甲苯; 合成 |
| 中图分类号：TQ241.1+5 文献标识码：A 文章编号：1009-9212(2003)05-0023-02 |
|
| The Synthesis of 2-chloro-6-fluorotoluene |
| LIU Li-rong~1; WANG Yue-jun~2; etc （1. Department of Chemical Engineering of Huaihai Instiute of Technology; Lianyungang 222005; China; 2.School of Shijiazhuang University of Economy and Trade; Shijiazhuang Hebei 53300; China） |
| Abstract：The synthesis method of 2-chloro-6-fluorotoluene was studied. Iron powder was used as reducer ,and 2-chloro-6-nitrotoluene was reduced to 3-chloro-2-methyloniline by being warmed in ferrous chloride aqueous solution.According to the reaction of Balz-schieman, 3-chloro-2-methyloniline was diazoed and cranked out diazo salt of fluoroboric acid, then it was decomposed to 2-chloro-6-fluorotoluene at 140?℃.The productive percentage is 67.98% by gas phase chromaogtraph. The purity of production is 99.2%. The synt... |
| Key words：chloro-6-fluorotoluene; 2-chloro-6-nitrotolu-ene; synthesis |
|
收稿日期：2002-12-18
|
| 阅读全文 |
|