| 第 33 卷第 6 期 |  | Vol. 33 No. 6 | | 2003 年 12 月 | Dec 2003 |
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所属栏目：其它
2-氰基-4-甲基联苯的合成研究 |
| 余红霞(武汉化工学院化工与制药学院; 湖北武汉) |
| 摘 要：以溴化亚铜为催化剂,将邻苯甲腈与对溴甲苯偶联制备了合成沙坦类药物的关键中间体2-氰基-4'-甲基联苯,收率50%。 |
| 关键词：2-氰基-4'-甲基联苯; 合成; 溴化亚铜 |
| 中图分类号：TQ243.3 文献标识码：A 文章编号：1009-9212(2003)06-0040-01 |
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| The Synthesis of 2-Cyano-4’-Methyl Phenylbenzene |
| YU Hong xia.（School of Chemical Technology & Pharmaceutics; Wuhan Institute of Chemical Technology; Wuhan Hubei 430073; China） |
| Abstract：cyano 4' methyl phenylbenzene, a key intermediate of Sartan drug, was synthesized from 4 bromotoluene and 2 bromobenzonitrile in the present of cuprous bromide as a catalyst. The yield is 50%. |
| Key words：cyano-4'-methyl phenylbenzene; synthesis; cuprous bromide |
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收稿日期：2003-06-23
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