第 34 卷第 1 期 Vol. 34 No. 1 2004 年 2 月 Feb 2004

所属栏目：其它 2,2-二(3-氨基-4-羟基)苯基丙烷的合成与结构表征

赵芳; 周莹; 孙汉洲; 胡云楚(中南林学院应用化学研究所; 湖南株洲)

摘　要：分别在Pd/C、FeOOH和FeCl3·6H2O/C三种不同催化剂存在下,由水合肼还原2,2 二(4 羟基 3 硝基)苯基丙烷(1)合成了2,2 二(3 氨基 4 羟基)苯基丙烷,筛选出成本低、收率高的理想催化剂为FeCl3·6H2O/C。当物料配比n(水合肼):n(1)=5:1,反应起始温度为70℃,反应时间为80min时,收率为93.0%。产物经重结晶纯化后,由元素分析、红外光谱、核磁共振谱和质谱对其结构进行了表征,确证了产物的结构。

关键词：2; 2-二（4-羟基-3-硝基）苯基丙烷; 2-二（3-氨基-4-羟基）苯基丙烷; 水合肼; 还原; FeCl36H2O/C催化剂

中图分类号：TQ241.4+8　　文献标识码：A　　文章编号：1009-9212(2004)01-0018-03

The Synthesis and Structural Characterization of 2,2-Bis(3-Amido-4-Hydroxyphenyl)-Propane

ZHAO Fang; ZHOU Ying; SUN Han-zhou; HU Yun-chu （Research Institute of Applied Chemistry; Central South Forestry Univeristy; Zhuzhou 412006; China）

Abstract：2,2-Bis(3-amido-4-hydroxyphenyl)-propane was synthesized by catalytic reduction of 2,2-Bis(4-hydroxy-3-nitrophenyl)-propane(1) with hydrazine hydrate in the presence of Pd/C,FeOOH and FeCl_3.6H_2O/C respectively. The results showed that the ideal catalyst was FeCl_3.6H_2O/C which gave high yield and had low cost. The yield was 93% when n (hydrazine hydrate):n(1)=5:1,temperature 70?℃, and reaction time 80?min. The structure of the product, which was crystallized, was certified by elementary analysis, IR,~1HN...

Key words：2; 2-Bis（3-amido-4-hydroxyphenyl）-propane; 2-Bis（4-hydroxy-3-nitrophenyl）-propane; hydrazine hydrate; catalytic reduction

基金项目：中南林学院青年科研基金(项目编号0480)

收稿日期：2003-09-15

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