| 第 34 卷第 3 期 |  | Vol. 34 No. 3 | | 2004 年 6 月 | Jun 2004 |
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所属栏目：其它
(S)-3-羟基丁内酯的合成 |
| 章小波; 蒋永祥; 汪劲松(浙江大学化学系; 杭州广林生物医药有限公司; 浙江杭州) |
| 摘 要：以乳糖为原料经分解酯化、官能团保护、酸化制得目标化合物。反应条件温和,原料易得,方法简单,具有一定的工业化应用前景。 |
| 关键词：（S）3羟基丁内酯; 苹果酸; 酯化; 合成 |
| 中图分类号：TQ225.24 文献标识码：A 文章编号：1009-9212(2004)03-0025-02 |
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| Synthesis of (S)-3-Hydroxybutyrolactone |
| ZHANG Xiao-bo; JIANG Yong-xiang; WANG Jin-song （1. Department of Chemistry; Zhe jiang University; Hangzhou 310027; China; 2. Hangzhou Great Forest Biomedical Co.Ltd.; Hangzhou 310028; China） |
| Abstract：Use lactose as the raw material, the (s)-3-hydroxybutyrolactone was obtained through reaction steps of decomposition, esterification, protection of function group, acidification. Not only the raw material was easily obtained but the condition was more moderate and the synthesis way was simple, which make it more suitable for industrial process. |
| Key words：（S）-3-Hydroxybutyrolactone; Malic Acid; Esterification; Synthesis |
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收稿日期：2003-12-12
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