| 第 34 卷第 4 期 |  | Vol. 34 No. 4 | | 2004 年 8 月 | Aug 2004 |
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所属栏目：其它
四氯化锡催化合成富马酸二甲酯 |
| 肖新荣; 付仕福; 曹徐涛; 黄增勇; 赵成祥(南华大学化学化工学院; 湖南衡阳) |
| 摘 要：以四氯化锡为催化剂,浓磷酸、硫脲、溴化钠为辅助催化剂组成混合物催化剂。用马来酸酐和甲醇为原料"一锅法"合成富马酸二甲酯。酯化反应的优惠工艺条件:四氯化锡1 0g,浓磷酸2 0ml,硫脲1 0g,溴化钠1 0g,马来酸酐与甲醇的质量比为1∶7,回流反应时间2 5h,收率达82 5%。该法以四氯化锡取代传统液体酸浓硫酸和浓盐酸,具有反应时间短,收率高,对设备无腐蚀性,对环境污染小的特点。 |
| 关键词：四氯化锡; 硫脲; 磷酸; 溴化钠; 马来酸酐; 富马酸二甲酯 |
| 中图分类号：O643.32 文献标识码：A 文章编号：1009-9212(2004)04-0058-02 |
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| Synthesis of Dimethyl Fumarate Catalyted by SnCl_4·5H_2O |
| XIAO Xin-rong; FU Shi-fu; CAO Xu-tao; HUANG Zen-yong; ZHAO Chen-xiang （Nanhua University; Hengyang 421001; China） |
| Abstract：The dimethyl fumarate was synthesized by one-step from maleic anhydride and methanol in presence of mixed catalyst composed of SnCl_4·5H_2O, concentrated phosphoric acid,sulfourea and sodium brominates. The optimum conditions are as follow:SnCl_4·5H_2O 1.0?g, concentrated phosphoric acid 2.0?ml, sulfourea 1.0?g, sodium brominates 1.0?g, the molar ratio of maleic anhydrid to methanol is 1∶7,the reaction time is 2.5?h, the yield of product is over 83.5%, the method has advantages of short reaction time,high y... |
| Key words：SnCl_4·5H_2O; maleic anhydride; dimethyl fumarate; phosphoric acid; sulfourea; sodium brominates |
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收稿日期：2004-03-12
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