| 第 34 卷第 4 期 |  | Vol. 34 No. 4 | | 2004 年 8 月 | Aug 2004 |
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所属栏目：其它
相转移催化氧化合成氯代苯甲酸 |
| 吴美芝; 曾明; 熊立武; 李晓如(湖南科技职业学院; 湖南长沙) |
| 摘 要：研究了以季铵盐A 1为催化剂,KMnO4作氧化剂,催化氧化邻、对位氯代甲苯合成邻、对位氯代苯甲酸,考察了不同的相转移催化剂的催化活性、催化剂的用量、反应温度、反应时间、KMnO4用量、水的用量等对反应的影响。优化反应条件:反应物料比为,氯代甲苯∶KMnO4为∶A 1∶H2O≈1∶2.6∶0.05∶300(mol),反应温度为93℃,反应时间为2.5h,在中性条件下进行反应,邻、对位氯代苯甲酸的收率分别可达76.4%、76.9%。实验结果表明,季铵盐A 1对此反应是一种优良的相转移催化剂。 |
| 关键词：相转移催化氧化; 季铵盐A1; 高锰酸钾; 氯代甲苯; 氯代苯甲酸 |
| 中图分类号：TQ245.3 文献标识码：A 文章编号：1009-9212(2004)04-0042-03 |
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| Phase Transfer Catalytic Synthesis of Chlorobenzoic Acid With Quaternary Ammonium Salt A-1 |
| WU Mei-zhi; ZENG Ming; XIONG Li-wu; LI Xiao-ru （Hunan Vocational College of Science & Technology; Changsha 410118; China） |
| Abstract：The catalytic synthesis of o-,p-chlorobenzoic aicd with phase transfer catalyst(PTC), quaternaty ammonium salt A-1,was reported. The effects of different factors,such as PTC activity and amount,reaction temperature and time, the amount of KMnO4 and H_2O, on the yield of chlorobezoic acid were investigated. The optimal reaction conditions were that the mole ratio of chlorotoluene to KMnO_4 to A-1 to H_2O was about 1∶2.6:∶.05∶300,the reaction temperature and time were 93?℃ and 2.5?h respectively and the react... |
| Key words：phase trasfer catalytic oxidation; quaternary ammonium salt-1; o-; p-chloroluene; p-chlorobenzoic acid; potassium permanganate |
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收稿日期：2004-06-14
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