| 第 34 卷第 4 期 |  | Vol. 34 No. 4 | | 2004 年 8 月 | Aug 2004 |
|
所属栏目：其它
盖布瑞尔合成法制备N-(2-羟乙基)-邻苯二甲酰亚胺 |
| 李建; 刘裕立; 李强军; 周光红; 杨军(湖南株洲时代新材料科技股份有限公司; 湖南株洲) |
| 摘 要：报道了通过盖布瑞尔合成法制备N (2 羟乙基) 邻苯二甲酰亚胺。以DMF为溶剂,邻苯二甲酰亚胺钾盐与氯乙醇在90℃下反应12h,N (2 羟乙基) 邻苯二甲酰亚胺的收率为86%。讨论了反应温度、反应时间、物料比例以及不同溶剂对反应收率的影响。该方法操作简便,实验条件温和,后处理简便,适合N (2 羟乙基) 邻苯二甲酰亚胺的实验室制备。 |
| 关键词：盖布瑞尔合成法; N-（2-羟乙基）-邻苯二甲酰亚胺; 邻苯二甲酰亚胺钾盐; 氯乙醇 |
| 中图分类号：TQ225.26 文献标识码：A 文章编号：1009-9212(2004)04-0031-02 |
|
| Synthesis of N-(2-Hydroxyethyl)phthalimide via Gabriel Method |
| LI Jian; LIU Yu-li; LI Qiang-jun; ZHOU Guang-hong; YANG Jun （Zhuzhou Times New Material Technology Co.; Ltd.Zhuzhou 412007; China） |
| Abstract：The synthesis of N-(2-hydroxyethyl)phthalimide via Gabriel synthesis method was reported. Potassium phthalimide reacted with 2-chloroethanol under 90?℃ or 12?h in DMF solvent, and the isolation yield was about 86%. The influences of reaction temperature,time,ratio of reactants,and solvent on the yields were discussed.The manipulation of this method was simple and it was easy to work up,which had its advantage on preparation of N-(2-hydroxyethyl)phthalimide on labortory scale. |
| Key words：gabriel synthesis; N-（2-hydroxyethyl）phthalimide; potassium phehalimide; 2-chloroethanol |
|
收稿日期：2004-01-06
|
| 阅读全文 |
|