第 35 卷第 1 期 Vol. 35 No. 1 2005 年 2 月 Feb 2005

所属栏目：其它 2-苯亚甲基肼基苯甲酸-4-磺酸的合成研究

袁其亮; 沈德隆; 刘会君; 钱捷; 付庆(浙江工业大学化材学院; 浙江杭州)

摘　要：以2-氨基苯甲酸-4-磺酸为原料,经过重氮化,还原反应生成-2-羧基苯肼-5-磺酸,再与苯甲醛缩合,合成2-苯亚甲基肼基苯甲酸-4-磺酸。反应总收率约 90%。产物结构经 H1NMR和MS表征。

关键词：2-苯亚甲基肼基苯甲酸-4-磺酸; 2-羧基苯肼-5-磺酸; 2-氨基苯甲酸-4-磺酸; 合成

中图分类号：TQ612.9　　文献标识码：A　　文章编号：1009-9212(2005)01-0058-02

Synthesis of 2-[(phenylmethylene)hydrazino]-4-sulfobenzoic acid

YUAN Qi-liang; SHEN De-long; LIU Hui-jun; QIAN Jie; FU Qing（College of Chemical Engineering and Materials Science; Zhejiang University of Technology; Hangzhou 310014; China）

Abstract：carboxyphenylhydrazine-5-sulfonic acid was synthesized through diazotization and reduction of 2-amino-4-sulfobenzoic acid, and then condensed with benzaldehyde to obtain 2-\[(phenylmethylene)- hydrazino\]-4-sulfobenzoic acid. The total yield is about 90%. The product structure was confirmed by H~(1)NMR and MS.

Key words：phenylmethylene）hydrazino\]-4-sulfobenzoic acid; 2-carboxyphenylhydrazine-5-sulfonic acid; 2-amino-4-sulfobenzoic acid; synthesis

基金项目：南京大学分析测试基金资助项目(CA3 3).

收稿日期：2004-11-26

阅读全文