| 第 35 卷第 2 期 |  | Vol. 35 No. 2 | | 2005 年 4 月 | Apr 2005 |
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所属栏目：其它
偕二溴环丁烷的合成 |
| 罗耀华; 林丹; 蒋玉仁; 刘佳佳(湖南大学衡阳分校化工系; 中南大学化学化工学院; 湖南衡阳; 湖南长沙) |
| 摘 要：以CH2(COOEt)2为原料,经烷基化、还原、磺酰化、环化、水解和脱羧溴置换六步反应,合成了烃基为苯基、正丁基和乙基的三种1,1二溴3烃基环丁烷化合物。结果表明合成操作简便,条件易控制、提出的合成路线可行。 |
| 关键词：1; 1-二溴-3-烃基环丁烷; 丙二酸二乙酯; 合成 |
| 中图分类号：TQ231.1 文献标识码：A 文章编号：1009-9212(2005)02-0032-03 |
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| Synthesis of 1,1-Dibromocyclobutanes |
| LUO Yao- hua;LIN-Dan;JIANG Yu-ren;LIU Jia-jia(1.Department of Chemistry;Hengyang College of Hunan university;Hengyang 421001; China;2.College of Chemistry and Chemical Engineering; Central South University; Changsha 410083;China) |
| Abstract：The synthesis of cyclobutane derivatives including 1,1-dibromo-3-phenylcyclobutane, 1,1-dibromo-3-ethylcyclobutane and 1,1-dibromo-3-ethylcyclobutane was studied in this paper. The synthesis routes involves such reactions as alkylation of diethyl malonate, reduction of ester, sulfonylation of alcohol, cyclization of sulfonylate and diethyl malonate, hydrolysis of ester and substitution of carboxyl group with bromine. The results show that the suggested synthesis method is simple, convenient and feasible to ... |
| Key words：1; 1-dibromo-3-alkylcyclobutanes; diethyl malonate; synthesis |
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收稿日期：2004-12-12
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