第 35 卷第 3 期 Vol. 35 No. 3 2005 年 6 月 Jun 2005

所属栏目：其它 α,α-二苯基-4-哌啶甲醇催化氢化合成工艺研究

蒋崇文; 何德文(中南大学化学化工学院; 湖南长沙)

摘　要：研究了催化氢化法合成α,α-二苯基-4-哌啶甲醇的工艺。以Pt/C为催化剂,考察了反应溶剂,压力,反应时间和催化剂添加比例对催化加氢反应的影响。在优惠的工艺条件下,α,α-二苯基-4-哌啶甲醇的收率可达92.4%,产品纯度为98.8%。

关键词：催化加氢; α; α-二苯基-4-哌啶甲醇; 合成

中图分类号：TQ46　　文献标识码：A　　文章编号：1009-9212(2005)03-0022-02

Synthesis of α,α-diphenyl-4-piperidinomethanol by catalytic Hydrogenation

JIANG Chong-wen; He De-wen（School of Chemistry and Chemical Engineering of Central South University; Changsha 410083; China）

Abstract：A novel technology of hydrogenation for synthesizing the α, α-diphenyl-4-piperidinomethanol was proposed by using Pt/C catalyst. The effects of solvents, pressure, temperature, catalyst amount and reaction time on the yield were investigated. Under the optimum reaction condition, the result showed that the yield can reach 92.4% and the purity was up to 98.8%.

Key words：catalytic hydrogenation; α; α-diphenyl-4-piperidinomethanol; synthesis

收稿日期：2005-01-05

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