第 35 卷第 3 期 Vol. 35 No. 3 2005 年 6 月 Jun 2005

所属栏目：其它 4、6-二甲氧基-2-甲砜基嘧啶的合成研究

邓继勇; 林原斌(湖南工程学院化学化工系湖南湘潭; 湘潭大学化学学院; 411104; 湖南湘潭)

摘　要：以硫脲、丙二酸二甲酯为原料,经缩合、O-烷基化和氧化反应合成了4、6-二甲氧基-2-甲砜基嘧啶,产品总收率59.1%,纯度96.0%。通过熔点测定、红外光谱、元素分析验证了中间体及目标分子结构。

关键词：嘧啶衍生物; 除草剂中间体; 合成

中图分类号：TQ254.1　　文献标识码：A　　文章编号：1009-9212(2005)03-0009-02

Synthesis of 4,6-Dimethoxyl-2-methylsulfonyl-pyrimidine

DENG Ji-yong~（1; 2）; LIN Yuan-bin~（2）（1.Chemistry and Engineering Department of Hunan Engineering Institute; Xiangtan 411104; China2.Chemistry Department of Xiangtan University; China）

Abstract：4,6-Dimethoxyl-2-methylsulfonyl-pyrimidine was synthesized in sequence of condensation, O-methylation and oxidation reaction using dimethyl malonate and thiourea as main materials. The total yield and the purity of product is 59.1% and 96%, respectively. The structure of target compound and its intermediates were confirmed by measurement of melt-point, IR and elementary analysis.

Key words：pyrimidine derivate; herbicidal agent medium; synthesis

收稿日期：2004-11-26

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