| 第 35 卷第 6 期 |  | Vol. 35 No. 6 | | 2005 年 12 月 | Dec 2005 |
|
所属栏目：农药及中间体
4-(4-甲基苯氧基)苄胺合成研究 |
| 戴健; 段湘生; 聂萍(湖南化工研究院; 湖南长沙) |
| 摘 要：以对氯苯甲腈,对甲酚为起始原料,经醚化、还原两步合成4-(4-甲基苯氧基)苄胺。详细考察了缚酸剂、催化剂及氨水的影响,得到了产品合成优惠条件:n｛4-(4-甲基苯氧基)苯甲腈｝n∶(催化剂)n∶(氨水)=10∶.78～0.91.∶1,反应温度20～35℃,反应至原料消失。总收率(以对氯苯甲腈计)72%,产品含量96.5%。 |
| 关键词：4-（4-甲基苯氧基）苄胺; 对氯苯甲腈; 对甲酚 |
| 中图分类号：TQ246 文献标识码：A 文章编号：1009-9212(2005)06-0035-02 |
|
| Synthesis of the 4-(4-methylphenoxy)benzylamine |
| DAI Jian; DUAN Xiang-sheng; NIE Ping（Hunan Research Institute of Chemical Industry; Changsha 410007; China） |
| Abstract：Four new glucosyl esters of all-trans-aritinoic acid were synthesized by the reaction of all-trans-aritinoic acid with O-acetylglucopyranosyl bromide or O-acetylgalactopyranosyl bromide,O-acetylgalactopyranosyl bromide,O-acetylgalactopyranosyl bromide in the presence of sodium carbonate and Bu4NBr.Their structures were confirmed by IR、1H NMR and MS. |
| Key words：all-trans-aritinoic acid; glycosyl esters; synthesis; characterization |
|
收稿日期：2005-09-25
|
| 阅读全文 |
|