第 35 卷第 6 期 Vol. 35 No. 6 2005 年 12 月 Dec 2005

所属栏目：专论与综述 2H-1,4-苯并噁嗪类化合物合成研究进展

闵忠诚; 杨道武; 谌伟民; 张泉; 黄明智(华中师范大学; 长沙理工大学化学与环境工程系; 湖北武汉; 湖南长沙; 湖南化工研究院)

摘　要：综述了不同取代基的2H-1,4-苯并噁嗪类化合物的合成方法。可以概括为两大类,其一以邻胺基苯酚或间卤苯酚为原料,与不同的-α卤代酸或酯反应,反应中不需要催化剂,在工业生产中普遍采用;另一类是用钯作催化剂,能扩大化合物的类型,并可选择性合成光学活性物质。

关键词：2H-1; 4-苯并噁嗪; 合成; 进展

中图分类号：TQ254.19　　文献标识码：A　　文章编号：1009-9212(2005)06-0007-04

Progress in synthesis of 2H-1,4-benzoxazine derivates

MIN Zhong-cheng;Yang Dao-wu;CHEN Wei-min;ZHANG Quan;HUANG Ming-zhi(Central China Normal University;Department of Chemistry and Environment Engineering;Changsha University of Science&Technology;Hunan Research Institute of Chemical Industry)

Abstract：Synthesis methods of 2H-1,4-benzoxazine derivatives were reviewed in this paper.These methods could be classified into two classes: one was the reaction of o-aminophenol or m-halophenol with different α-halogenated acids or esters without any catalyst,which was used widely in industrial production;the other could enlarge compounds' classes via palladium as catalyst,and give optically active compound.

Key words：2H-1; 4-Benzoxazine; Synthesis; Progress

基金项目：国家自然科学基金资助项目(20372021);湖南省自然科学基金资助项目(03JJY3018)

收稿日期：2005-05-12

阅读全文