| 第 36 卷第 1 期 |  | Vol. 36 No. 1 | | 2006 年 2 月 | Feb 2006 |
|
所属栏目：专论与综述
芳基硼酸在有机合成中的应用 |
| 李英奇; 伍佑华; 彭雨春(湘潭大学; 湖南湘潭) |
| 摘 要：芳基硼酸作为一种重要的中间体,在有机合成中的应用相当广泛。Suzuki偶联反应是合成联芳基结构最有效的方法之一,近年许多用于芳基硼酸与各种卤代芳烃偶合的催化剂相继被开发。芳基硼酸与苯酚在Cu(OAc)2和NEt3存在时用于合成二芳基醚,与胺的偶联是合成C-N键的有效方法,与,α-β不饱和体系的1,4-共轭加成反应广泛用于β-取代羰基化合物的合成。反应采用相对无毒而又廉价的普通试剂,反应条件温和,产率高,立体选择性好。综述了芳基硼酸在联芳基合成、二芳基醚合成、芳香胺合成和催化加成反应中的应用。 |
| 关键词：芳基硼酸; 配体; 偶联反应; 二芳基醚; 催化加成反应 |
| 中图分类号：TQ128+54 文献标识码：A 文章编号：1009-9212(2006)01-0014-04 |
|
| Application of Arylboronic Acid in Organic Synthesis |
| LI Ying-qi; WU You-hua; PENG Yu-chun（Xiangtan University; Xiangtan 411100; China） |
| Abstract：The Applications of Arylboronic Acid in biaryl synthesis,synthesis of diaryl ethers,synthesis of aromatic amines and catalytic addition reactions were summarized.Suzuki cross-coupling reaction is one of the most efficient methods for the construction of Caryl-Caryl bonds.In recent years,Various efficient catalyst precursors have been developed that allow aryl iodides,bromides,and chlorides to be effectively coupled with aryl boronic acids.Moreover,Ni-based catalysts have also been successfully used for the ... |
| Key words：arylboronic acid; ligand; cross-coupling reaction; diaryl ether; catalytic addition reaction |
|
收稿日期：2005-09-02
|
| 阅读全文 |
|