| 第 36 卷第 2 期 |  | Vol. 36 No. 2 | | 2006 年 4 月 | Apr 2006 |
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所属栏目：有机合成原料
双氯乙酸聚乙二醇酯的合成研究 |
| 常军; 郑玉斌; 段久芳; 尚宏周; 吕婵婷(大连理工大学高分子材料与工程系; 辽宁大连) |
| 摘 要：采用一氯乙酸与不同分子量的聚乙二醇发生酯化反应,合成了一系列端基含有活性氯的氯乙酸聚乙二醇酯,并采用正交实验法确定了酯化反应的优惠工艺路线。实验表明,在温度为80℃,催化剂w(浓硫酸)=4%(反应物),n(聚乙二醇)∶n(氯乙酸)=1∶8,反应时间为6h的反应条件下,产品收率42%。 |
| 关键词：聚乙二醇; 一氯乙酸; 酯化反应; 正交实验 |
| 中图分类号：TQ225.24 文献标识码：A 文章编号：1009-9212(2006)02-0047-03 |
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| Catalytic Synthesis of Ester from Acetic Acid and Polyethylene Glycol |
| CHANG Jun; ZHENG Yu-bin; DUAN Jiu-fang; SHANG Hong-zhou; LU Chan-ting （Department of Polymer Materials & Engineering; Dalian University of Technology; Dalian 116012; China） |
| Abstract：A series of novel polyethylene glycol derivatives was synthesized by esterification of chloroacetic acid with polyethylene glycol. Based on the result of orthogonal experiment,the optimum condition of the esterification reaction of chloroacetic acid with polyethylene glycol was determined. Experimental results showed that the reaction temperature was 80 ℃,the amount of catalyst was 4%(wt) of the reactant,the mole ratio of polyethylene glycol and chloroacetic acid was 1 ∶ 8,reaction time was 6 h,the maximum ... |
| Key words：polyethylene glycol; chloroacetic acid; esterfication; orthogonal experiment |
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收稿日期：2005-12-13
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