| 第 31 卷第 3 期 |  | Vol. 31 No. 3 | | 2001 年 6 月 | Jun 2001 |
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所属栏目：其它
二硫化钠法合成巯基乙酸的研究 |
| 符剑刚; 钟宏(中南大学化学化工学院) |
| 摘 要：概述了巯基乙酸的用途、合成方法 ,研究了二硫化钠法合成巯基乙酸的主要影响因素。实验从硫化钠、硫磺等基本原料出发 ,首先制得二硫化钠溶液 ,然后将二硫化钠同氯乙酸钠反应合成二硫代甘醇酸 ,最后用硫化钠溶液还原得到巯基乙酸。试验探讨了反应物料配比、反应温度、pH值、反应时间等因素对反应转化率的影响 ,实验结果表明该法的转化率可达 96 %左右 ,其具体反应条件如下 :硫化钠∶硫∶氯乙酸钠 (mol) =1.2∶1.4 4∶1.0 0 ,pH值 =7.5,合成二硫代甘醇酸的温度为 35℃ ,时间为 30min |
| 关键词：巯基乙酸; 二硫化钠; 合成 |
| 中图分类号：TQ225.27 文献标识码：A 文章编号：1009-9212(2001)03-0021-03 |
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| Synthesis of Thioglycolic Acid by Sodium Disulfide Method |
| FU Jian gang; ZHONG Hong （College of Chemistry and Chemical Engineering to Central South University; Changsha 410083; China） |
| Abstract：The application and synthesis of thioglycolic acid were reviewed. Thioglycolic acid was synthesized by sodium disulfide method. In the experiment, sodium disulfide was firstly prepared from sodium sulfide and sulfur, and then (SCH 2COONa) 2 was synthesized with ClCH 2COONa and sodium disulfide, in the last step, sodium sulfide aqueous solution, as a kind of reducer, was used to reduce (SCH 2COONa) 2. The effects of reaction temperature, reactant ratio, reaction time, pH value etc., were investigated th... |
| Key words：thioglycolic acid; sodium disulfide; synthesis |
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收稿日期：2001-03-27
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