| 第 37 卷第 4 期 |  | Vol. 37 No. 4 | | 2007 年 8 月 | Aug 2007 |
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所属栏目：医药及中间体
微波辐射分子筛催化合成乙酰水杨酸的研究 |
| 刘 鸿，黄 华
（惠州学院化学工程系，广东 惠州 516001） |
| 摘 要：介绍了一种采用微波辐射技术、分子筛催化合成乙酰水杨酸的方法，探讨了不同反应条件对产物收率的影响，实验结果表明：当n（水杨酸） ∶ n（乙酸酐）=1 ∶ 2.0、催化剂的用量为水杨酸质量的5%、微波辐射功率为200 W、辐射时间为2.5 min时，乙酰水杨酸的收率可达95.1%. |
| 关键词：微波辐射；分子筛；催化；合成；乙酰水杨酸 |
| 中图分类号：O621.25 文献标识码：A 文章编号：1009-9212（2007）04- 0027-02 |
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| Synthesis of Acetylsalicylic Acid by Microwave Irradiation with Molecular Sieve as Catalyst |
| LIU Hong，HUANG Hua
（Department of Chemistry Engineering，Huizhou University，Huizhou 516001，China） |
| Abstract：A method of synthesis of acetylsalicylic acid by microwave irradiation with molecular sieve as catalyst was introduced，the effects of different reaction conditions on yield of the product were discussed，the experimental results showed that，the yield of acetylsalicylic acid reached 95.3% when molar ratio of salicylic acid to acetic acid anhydride was 1 ∶ 2.0，the molecular sieve catalyst amount was 5% of salicylic acid，the microwave power was 200 W and the reaction time was 2.5 min. |
| Key words：microwave irradiation；molecular sieve；catalysis；synthesis；acetylsalicylic acid |
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作者简介：刘 鸿（1972-），男，江西新余人，硕士，主要从事精细有机合成和高分子合成。（E-mail：hzlh@hzu.edu.cn）
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收稿日期：2007-06-01
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